Honokiol kinase inhibitor product blog
Tags: Kinase Inhibitor; Honokiol; Honokiol kinase inhibitor;
The Honokiol n/a (Catalog #MBS8506297) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the Honokiol with the following immunoassay(s):
Testing Data
Honokiol is a biphenolic compound present in the cones, bark, and leaves of Magnolia grandifloris. It inhibits phosphorylation of Akt, p44/42 mitogen-activated protein kinase (MAPK), and src. Additionally, honokiol modulates the nuclear factor kappa B (NF-kappaB) activation pathway, an upstream effector of vascular endothelial growth factor (VEGF), cyclooxygenase 2 (COX-2), and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides. Honokiol has been shown to promote neurite outgrowth and have neuroprotective effects in rat cortical neurons. [1].
Solubility: DMSO >=53mg/mL - Water >=53mg/mL - Ethanol <1mg/mL. Formula: C18H18O2
CAS Number: 35354-74-6.