HMGN3 blocking peptide product blog
Tags: Blocking Peptide; HMGN3; HMGN3 blocking peptide;
The HMGN3 hmgn3 (Catalog #MBS9222019) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The HMGN3 hmgn3 product has the following accession number(s) (GI #23831169) (NCBI Accession #Q15651.2) (Uniprot Accession #Q15651). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function (By similarity).
Cellular Location: Nucleus. Tissue Location: Expressed in kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate and uterus. Low expression in liver, spleen, placenta and ovaries. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Disease Models, Animal, Liver Diseases, Liver Neoplasms are some of the diseases may be linked to HMGN3 Antibody (N-term) Blocking Peptide. Blood, Brain, Eye, Liver, Muscle, Ovary, Pancreas, Skin, Thyroid, Uterus tissues are correlated with this protein.