|The GSTM2 gstm2 (Catalog #MBS635357) is a Reagent and is intended for research purposes only. The product is available for immediate purchase.
Suitable for use for purification of GST-fusion proteins or other glutathione- binding proteins. Researchers should empirically determine the suitability of the GSTM2 gstm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The GSTM2 gstm2 product has the following accession number(s) (GI #215277000) (NCBI Accession #NP_001135840.1) (Uniprot Accession #P28161). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The Glutathione-S-Transferase (GST) gene fusion system has been widely used for the over expression of foreign genes in E. coli. The expressed fusion protein with a GST tail can be easily purified by affinity chromatography on Glutathione-Sepharose beads from the bacterial lysate. Glutathione-Sepharose is designed for the purpose of purification of such GST fusion proteins or any other kinds of glutathione binding proteins. This formulation exhibits excellent binding capacity, high flow rate, no significant loss of the glutathione ligand and a pH stability range of 2-10.
Storage Buffer: 0.01% Thimersol / ddH2O. Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Muscle, Ovary, Testis tissues are correlated with this protein. Breast Neoplasms, Carcinoma, Hepatocellular, Cardiovascular Diseases, Disease Models, Animal, Hypertension, Liver Diseases, Liver Neoplasms, Liver Neoplasms, Experimental, Neoplasms, Experimental, Precancerous Conditions are some of the diseases may be linked to Glutathione (Sepharose). GSTM2 also interacts with the following gene(s): GPX1, GPX4, GSTA2, GSTM1, GSTM3, GSTZ1. The following patways have been known to be associated with this gene.