GSPT2 blocking peptide product blog
Tags: Blocking Peptide; GSPT2; ERF3B; GSPT2 blocking peptide;
The GSPT2 gspt2 (Catalog #MBS9228331) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The GSPT2 gspt2 product has the following accession number(s) (GI #182647413) (NCBI Accession #Q8IYD1.2) (Uniprot Accession #Q8IYD1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Cellular Location: Cytoplasm. Tissue Location: Highly expressed in IUCC stage II colorectal cancer (CRC). Adenocarcinoma, Breast Neoplasms, Carcinoma, Hepatocellular, Chromosome Breakage, Hepatitis, Liver Diseases, Liver Neoplasms, Ovarian Neoplasms are some of the diseases may be linked to ERF3B Antibody (Center) Blocking Peptide. The following patways have been known to be associated with this gene. Blood, Brain, Liver, Mammary Gland, Prostate, Thyroid tissues are correlated with this protein.