|The GPRC5B gprc5b (Catalog #MBS9221721) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The GPRC5B gprc5b product has the following accession number(s) (GI #46396016) (NCBI Accession #Q9NZH0.2) (Uniprot Accession #Q9NZH0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
Cellular Location: Cell membrane; Multi-pass membrane protein Cytoplasmic vesicle membrane; Multi- pass membrane protein Note: Localized in the plasma membrane and perinuclear vesicles. Tissue Location: Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. Brain, Embryonic Tissue, Heart, Intestine, Kidney, Liver, Lung, Pancreas, Placenta, Vascular tissues are correlated with this protein. Acute Kidney Injury, Breast Neoplasms, Fibrosis, Inflammation, Necrosis, Weight Loss are some of the diseases may be linked to GPRC5B Antibody (C-term) Blocking Peptide. The following patways have been known to be associated with this gene.