|The GGA1 gga1 (Catalog #MBS9224646) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The GGA1 gga1 product has the following accession number(s) (GI #14548066) (NCBI Accession #Q9UJY5.1) (Uniprot Accession #Q9UJY5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
Cellular Location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Tissue Location: Ubiquitously expressed. GGA1 also interacts with the following gene(s): ARF1, ARF3, ARF6, BACE1, IGF2R, RABEP1, SYNRG. Blood, Bone, Brain, Connective Tissue, Heart, Intestine, Kidney, Lung, Muscle, Nerve tissues are correlated with this protein. The following patways have been known to be associated with this gene. Body Weight Changes, Chromosome Aberrations, Disease Models, Animal, Kidney Diseases, Nervous System Diseases, Weight Gain, Weight Loss are some of the diseases may be linked to GGA1 Antibody (N-term) Blocking Peptide.