GALNT11 blocking peptide product blog
Tags: Blocking Peptide; GALNT11; GLT11; GALNT11 blocking peptide;
The GALNT11 galnt11 (Catalog #MBS9223042) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The GALNT11 galnt11 product has the following accession number(s) (GI #51316030) (NCBI Accession #Q8NCW6.2) (Uniprot Accession #Q8NCW6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1. O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO). Polypeptide N- acetylgalactosaminyltransferases catalyze the transfer of an N- acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1. Not involved in glycosylation of erythropoietin (EPO).
Cellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Tissue Location: Highly expressed in kidney. Expressed at intermediate level in brain, heart and skeletal muscle. Weakly expressed other tissues. In kidney, it is strongly expressed in tubules but not expressed in glomeruli. The following patways have been known to be associated with this gene. Blood, Heart, Kidney, Lung tissues are correlated with this protein. Abnormalities, Multiple, Edema, Heart Defects, Congenital, Heart Diseases, Kidney Diseases, Necrosis are some of the diseases may be linked to GLT11 Antibody (N-term) Blocking Peptide.