FOLR2 blocking peptide product blog
Tags: Blocking Peptide; FOLR2; FOLR2 blocking peptide;
The FOLR2 folr2 (Catalog #MBS9225482) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The FOLR2 folr2 product has the following accession number(s) (GI #116241366) (NCBI Accession #P14207.4) (Uniprot Accession #P14207). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Cellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Tissue Location: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues. Bone, Connective Tissue, Intestine, Kidney, Lung, Muscle, Parathyroid, Placenta, Spleen, Uterus tissues are correlated with this protein. Adenocarcinoma, Disease Models, Animal, Inflammation, Kidney Diseases, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Nervous System Diseases, Neural Tube Defects, Ovarian Neoplasms are some of the diseases may be linked to FOLR2 Antibody (N-term) Blocking Peptide. The following patways have been known to be associated with this gene.