FLCN blocking peptide product blog
Tags: Blocking Peptide; FLCN; FLCN blocking peptide;
The FLCN flcn (Catalog #MBS9227771) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The FLCN flcn product has the following accession number(s) (GI #74751276) (NCBI Accession #Q8NFG4.1) (Uniprot Accession #Q8NFG4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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May play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
Cellular Location: Cytoplasm. Nucleus. Note: Mainly localized in the nucleus. Colocalizes with FNIP1 and FNIP2 in the cytoplasm. Tissue Location: Expressed in most tissues tested, including skin, lung, kidney, heart, testis and stomach. Birt-Hogg-Dube Syndrome, Breast Neoplasms, Cardiovascular Diseases, Disease Models, Animal, Hyperplasia, Kidney Diseases, Liver Diseases, Liver Neoplasms, Nervous System Diseases, Pneumothorax are some of the diseases may be linked to FLCN Antibody (C-term) Blocking Peptide. Blood, Bone, Brain, Kidney, Liver, Ovary, Placenta, Skin, Testis, Uterus tissues are correlated with this protein. FLCN also interacts with the following gene(s): CCND1, FNIP1, FNIP2, PKP4, TFE3. The following patways have been known to be associated with this gene.