|The FGF9 fgf9 (Catalog #MBS539551) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s FGF9 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the FGF9 fgf9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGF9 fgf9 product has the following accession number(s) (GI #391719) (NCBI Accession #BAA03572.1) (Uniprot Accession #P31371). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of FGF9 protein correspond ing to amino acids PLGEVGSYFG VQDAVPFGNV PVLPVDSPVL LNDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including FGF9 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: FGF9 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4.
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is 2 x 10^6 units/mg.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. Adenocarcinoma, Carcinoma, Non-Small-Cell Lung, Cardiovascular Diseases, Cleft Palate, Heart Diseases, Hyperplasia, Hypertrophy, Inflammation, Lung Diseases, Lung Neoplasms are some of the diseases may be linked to FGF9 protein. FGF9 also interacts with the following gene(s): FGF19, FGFR1, FGFR2, FGFR3, FGFR4, PDGFRA, PDGFRB, WNT4. Blood, Brain, Connective Tissue, Embryonic Tissue, Eye, Heart, Intestine, Kidney, Lung, Testis tissues are correlated with this protein. The following patways have been known to be associated with this gene.