|The FGF16 fgf16 (Catalog #MBS536556) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s FGF16 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the FGF16 fgf16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FGF16 fgf16 product has the following accession number(s) (GI #4503691) (NCBI Accession #NP_003859.1) (Uniprot Accession #O43320). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of FGF16 protein correspond ing to amino acids MAEVGGVFAS LDWDLHGFSS SLGNVPLADS PGFLNERLGQ IEGKLQRGSP TDFAHLKGIL RRRQLYCRTG FHLEIFPNGT VHGTRHDHSR FGILEFISLA VGLISIRGVD SGLYLGMNER GELYGSKKLT RECVFREQFE ENWYNTYAST LYKHSDSERQ YYVALNKDGS PREGYRTKRH QKFTHFLPRP VDPSKLPSMS RDLFHYR.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including FGF16 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: FGF16 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF16 signals through FGFR 2c and 3c. FGF16 plays a role in the development of the central nervous system.
Bioactivity: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is approximately 0.5 ng/ml, corresponding to a specific activity of approximately 2 x 10^6 units/mg.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. The following patways have been known to be associated with this gene. Carcinoma, Cardiomegaly, Heart Diseases, Heart Failure, Hemorrhage, Hyperglycemia, Hypertrophy, Lung Neoplasms, Ovarian Neoplasms, Weight Loss are some of the diseases may be linked to FGF16 protein.