FGB blocking peptide product blog
Tags: Blocking Peptide; FGB; FIBB; FGB blocking peptide;
The FGB fgb (Catalog #MBS9226117) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The FGB fgb product has the following accession number(s) (GI #399492) (NCBI Accession #P02675.2) (Uniprot Accession #P02675). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Cellular Location: Secreted. The following patways have been known to be associated with this gene. FGB also interacts with the following gene(s): F10, F13A1, FGA, FGG, ITGB3. Afibrinogenemia, Atherosclerosis, Brain Diseases, Cardiovascular Diseases, Hypertension, Inflammation, Kidney Diseases, Liver Diseases, Lung Neoplasms, Pain are some of the diseases may be linked to FIBB Antibody (N-term) Blocking Peptide. Bladder, Blood, Brain, Heart, Intestine, Kidney, Liver, Lung, Muscle, Pancreas tissues are correlated with this protein.