|The FAS fas (Catalog #MBS969349) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The FAS fas product has the following accession number(s) (GI #4507583) (NCBI Accession #NP_000034.1) (Uniprot Accession #P25445). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
RLSSKSVNAQ VTDINSKGLE LRKTVTTVET QNLEGLHHDG QFCHKPCPPG ERKARDCTVN GDEPDCVPCQ EGKEYTDKAH FSSKCRRCRL CDEGHGLEVE INCTRTQNTK CRCKPNFFCN STVCEHCDPC TKCEHGIIKE CTLTSNTKCK EEGSRSN.
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Please refer to the product datasheet for known applications of a given recombinant protein. We\'ve tested the Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (FAS) (Active) with the following immunoassay(s):
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Tumor necrosis factor receptor superfamily member 6 protein (FAS) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Species: Homo sapiens (Human)
Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cytotoxicity of Jurkat cells is between 10-15 ug/ml in the presence of 2 ng/ml of rHuFas Ligand. Storage Buffer: 0.2 um filtered PBS, pH 7.4,lyophilized
Endotoxin: Less than 1.0 EU/ug as determined by LAL method. The following patways have been known to be associated with this gene. FAS also interacts with the following gene(s): BID, CASP10, CASP8, CFLAR, FADD, FAF1, FASLG, MAP3K5, PTPN13, TRADD. Autoimmune Diseases, Disease Models, Animal, Fatty Liver, Heart Diseases, Hematologic Diseases, Inflammation, Liver Diseases, Necrosis, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to Recombinant Human Tumor necrosis factor receptor superfamily member 6 protein (FAS) (Active). Blood, Bone, Bone Marrow, Brain, Heart, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein.