ERVW-1 blocking peptide product blog
Tags: Blocking Peptide; ERVW-1; HERV (ERVWE1); ERVW-1 blocking peptide;
The ERVW-1 ervw-1 (Catalog #MBS9224751) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ERVW-1 ervw-1 product has the following accession number(s) (GI #47605755) (NCBI Accession #Q9UQF0.1) (Uniprot Accession #Q9UQF0). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).
Cellular Location: Transmembrane protein: Cell membrane; Single-pass type I membrane protein Syncytin-1: Virion. Tissue Location: Expressed at higher level in placental syncytiotrophoblast. Expressed at intermediate level in testis Seems also to be found at low level in adrenal tissue, bone marrow, breast, colon, kidney, ovary, prostate, skin, spleen, thymus, thyroid, brain and trachea. Both mRNA and protein levels are significantly increased in the brain of individuals with multiple sclerosis, particularly in astrocytes and microglia. Embryo Loss, Pregnancy Complications are some of the diseases may be linked to HERV (ERVWE1) Antibody (Center) Blocking peptide.