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EPAC1 blocking peptide product blog

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Posted on 2016-06-19 22:19:47 by mybiosource_staff
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Tags: EPAC1; Blocking Peptide; EPAC1 blocking peptide;
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The EPAC1 rapgef3 (Catalog #MBS543635) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s EPAC1 can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion.
Confocal Microscopy: 1:200
Immunocytochemistry: 1:200
Immunofluorescence: 1:200
Immunohistochemistry: 1:200
Western Blot: 1:500. Researchers should empirically determine the suitability of the EPAC1 rapgef3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The EPAC1 rapgef3 product has the following accession number(s) (GI #4079649) (NCBI Accession #AAD12740.1) (Uniprot Accession #O95398). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Antigenic Blocking Peptide Rap Guanine Nucleotide Exchange Factor 3 Mid-Region
Guanine nucleotide exchange factor for RAP1A and RAP2A small GTPases that are activated by binding cAMP.

EPAC1 rapgef3

Immunogen: Synthetic peptide corresponding to amino acids 526-541 of Epac1 protein, peptide was covalently modified.
Sequence: DHSVLTLQLQLPVTASVR
Expression: Widely expressed with highest levels in kidney, heart, thyroid and brain. Determinant: Mid-Region
Molecular Function: cAMP-binding; Nucleotide-binding
Structure: Interacts with PDE3B
Subcellular Location: Endomembrane system. The following patways have been known to be associated with this gene. EPAC1 also interacts with the following gene(s): ABCC8, PDE3B, PDE4A, RAP1A, RAP1B, RAP1GAP. Cardiovascular Diseases, Edema, Fibrosis, Heart Diseases, Heart Failure, Hypertrophy, Inflammation, Lung Diseases, Necrosis, Vascular Diseases are some of the diseases may be linked to Epac1 Peptide. Blood, Brain, Heart, Kidney, Lung, Muscle, Pancreas, Prostate, Umbilical Cord, Vascular tissues are correlated with this protein.
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