ENA78 recombinant protein product blog
Tags: Recombinant Protein; ENA78; ENA78 recombinant protein;
The ENA78 cxcl5 (Catalog #MBS539471) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s ENA78 can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the ENA78 cxcl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ENA78 cxcl5 product has the following accession number(s) (GI #471243) (NCBI Accession #CAA55355.1) (Uniprot Accession #P42830). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of ENA78 protein correspond ing to amino acids LRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including ENA78 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The Mouse homolog of ENA-78 is called LIX. The three naturally occurring variants of human ENA-78; ENA 5-78, ENA 9-78 and ENA 10-78, contain 74, 70, and 69 amino acid residues, respectively, and possess the same biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the \'ELR\' motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors.
Bioactivity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. Cardiovascular Diseases, Disease Models, Animal, Fibrosis, Inflammation, Liver Diseases, Lung Diseases, Lung Neoplasms, Necrosis, Pneumonia, Respiratory Tract Diseases are some of the diseases may be linked to ENA78 protein. The following patways have been known to be associated with this gene. ENA78 also interacts with the following gene(s): CCL19, CCL20, CCL5, CXCL10, CXCL11, CXCL12, CXCL13, CXCR1, CXCR2, CXCR3. Blood, Brain, Connective Tissue, Embryonic Tissue, Intestine, Kidney, Lung, Skin, Uterus, Vascular tissues are correlated with this protein.