EDN3 peptide product blog
Tags: Peptide; EDN3; Endothelin 3; EDN3 peptide;
The EDN3 edn3 (Catalog #MBS659041) is a Peptide produced from Synthetic peptide and is intended for research purposes only. The product is available for immediate purchase. The Endothelin 3 (Big) (1-41) (human) (Endothelin-3, EDN3, ET3, ET-3, MGC15067, MGC61498, Preproendothelin-3, PPET3) reacts with Human and may cross-react with other species as described in the data sheet.The EDN3 edn3 product has the following accession number(s) (GI #46370064) (NCBI Accession #NP_996917.1) (Uniprot Accession #P14138). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms, ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET\'s can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart and liver.
Sequence (linear): Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-Ile-Asn-Thr-Pro-Glu-Gln-Thr-Val-Pro-Tyr-Gly-Leu-Ser-Asn-Tyr-Arg-Gly-Ser-Phe-Arg-NH2. Brain, Connective Tissue, Ear, Eye, Heart, Intestine, Muscle, Nerve, Ovary, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene. EDN3 also interacts with the following gene(s): EDN1, EDNRA, EDNRB. Cardiovascular Diseases, Congenital central hypoventilation syndrome, Disease Models, Animal, Hirschsprung Disease, Hypertension, Kidney Diseases, Neoplasms, Nervous System Diseases, WAARDENBURG SYNDROME, TYPE 4A, Waardenburg syndrome, type 4 are some of the diseases may be linked to Endothelin 3 (Big) (1-41) (human) (Endothelin-3, EDN3, ET3, ET-3, MGC15067, MGC61498, Preproendothelin-3, PPET3).