|The EAAT2 slc1a2 (Catalog #MBS544484) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s EAAT2 can be used in a range of immunoassay formats including, but not limited to, Immunocompetition, Immunodepletion.
Dot Blot: 1:10,000
Western Blot: 1:500. Researchers should empirically determine the suitability of the EAAT2 slc1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The EAAT2 slc1a2 product has the following accession number(s) (GI #40254478) (NCBI Accession #NP_004162.2) (Uniprot Accession #P43004). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Antigenic Blocking Peptide Excitatory amino acid transporter 2
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Immunogen: Synthetic peptide corresponding to C terminal amino acids 550-574 of Human EAAT2.
Sequence: KVTLAANGKSADCSVEEEPWKREK. Molecular Function: Glutamate:sodium symporter activity, L-glutamate transmembrane transporter activity, sodium:dicarboxylate symporter activity
Subcellular Location: Membrane, multi-pass membrane protein. Blood, Brain, Eye, Kidney, Liver, Lymph Node, Muscle, Nerve, Placenta, Spinal Cord tissues are correlated with this protein. Amyotrophic Lateral Sclerosis, Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Epilepsy, Inflammation, Movement Disorders, Necrosis, Nervous System Diseases, Pain are some of the diseases may be linked to EAAT2 Peptide. EAAT2 also interacts with the following gene(s): ADORA1, GLUL, MTDH, SLC29A1.