DYRK1B blocking peptide product blog
Tags: Blocking Peptide; DYRK1B; DYRK1B blocking peptide;
The DYRK1B dyrk1b (Catalog #MBS9221956) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The DYRK1B dyrk1b product has the following accession number(s) (GI #9296963) (NCBI Accession #Q9Y463.1) (Uniprot Accession #Q9Y463). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
Cellular Location: Nucleus. Tissue Location: Highest expression in skeletal muscle, testis, heart and brain with little expression in colon or lung. Expressed in a variety of tumor cell lines. Blood, Brain, Embryonic Tissue, Kidney, Lung, Nerve, Ovary, Pancreas, Skin, Testis tissues are correlated with this protein. DYRK1B also interacts with the following gene(s): CCND1, CDKN1A, CDKN1B, DCAF7, HNF1A, RHOA. Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Diabetes Mellitus, Inflammation, Kidney Diseases, Lung Neoplasms, Neoplasms, Experimental, Ovarian Neoplasms, Pancreatic Neoplasms are some of the diseases may be linked to DYRK1B Antibody (Center) Blocking Peptide.