|The DOK5 dok5 (Catalog #MBS9227171) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The DOK5 dok5 product has the following accession number(s) (GI #26393190) (NCBI Accession #Q9P104.2) (Uniprot Accession #Q9P104). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Tissue Location: Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes. Kidney tissues are correlated with this protein. The following patways have been known to be associated with this gene. Fibrosis, Lung Neoplasms, Neoplasm Metastasis are some of the diseases may be linked to DOK5 Antibody (N-term) Blocking Peptide.