DHFR recombinant protein product blog
Tags: Recombinant Protein; DHFR recombinant protein; DHFR;
The DHFR dhfr (Catalog #MBS203372) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s DHFR can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the DHFR dhfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The DHFR dhfr product has the following accession number(s) (GI #4503323) (NCBI Accession #NP_000782.1) (Uniprot Accession #P00374). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MGSSHHHHHH SSGLVPRGSH MVGSLNCIVA VSQNMGIGKN GDLPWPPLRN EFRYFQRMTT TSSVEGKQNL VIMGKKTWFS IPEKNRPLKG RINLVLSREL KEPPQGAHFL SRSLDDALKL TEQPELANKV DMVWIVGGSS VYKEAMNHPG HLKLFVTRIM QDFESDTFFP EIDLEKYKLL PEYPGVLSDV QEEKGIKYKF EVYEKND.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given active protein. We\'ve tested the DHFR, 1-187aa, Human, His tag, E Coli (Bioactivity Validated) with the following immunoassay(s):
SDS-Page
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including DHFR are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Antigen Species: Human
Tag Information: His-tag. Biological Activity: Specific activity is > 3500 pmol/min/ug, and is defined as the amount of enzyme that converts 1.0 pmole of dihydrofolic acid to tetrahydrofolic acid per minute at pH 6.5 at 25C. The following patways have been known to be associated with this gene. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Ovary, Skin, Vascular tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Carcinoma, Squamous Cell, Cardiovascular Diseases, Cell Transformation, Neoplastic, Colorectal Neoplasms, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to DHFR, 1-187aa, Human, His tag, E Coli (Bioactivity Validated). DHFR also interacts with the following gene(s): E2F4, FPGS, MTHFD1, MTR, RBL1, SHMT1, SHMT2, SP1, TYMS.