DHFR blocking peptide product blog
Tags: DHFR; Blocking Peptide; Dhfr blocking peptide;
The DHFR dhfr (Catalog #MBS9229262) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The DHFR dhfr product has the following accession number(s) (GI #118992) (NCBI Accession #P00374.2) (Uniprot Accession #P00374). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.
Tissue Location: Widely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood Expression is higher in the adult brain than in the fetal brain. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Ovary, Skin, Vascular tissues are correlated with this protein. DHFR also interacts with the following gene(s): FPGS, MTHFD1, PCNA, SHMT1, SHMT2, SP1, SPR, TYMS. Adenocarcinoma, Carcinoma, Squamous Cell, Cardiovascular Diseases, Cell Transformation, Neoplastic, Colorectal Neoplasms, Disease Models, Animal, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases are some of the diseases may be linked to DHFR Blocking Peptide (N-term). The following patways have been known to be associated with this gene.