DERL1 blocking peptide product blog
Tags: Blocking Peptide; DERL1; DERL1 blocking peptide;
The DERL1 derl1 (Catalog #MBS9227826) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The DERL1 derl1 product has the following accession number(s) (GI #50400630) (NCBI Accession #Q9BUN8.1) (Uniprot Accession #Q9BUN8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome. May mediate the interaction between VCP and the degradation substrate. In case of infection by cytomegaloviruses, it plays a central role in the export from the ER and subsequent degradation of MHC class I heavy chains via its interaction with US11 viral protein, which recognizes and associates with MHC class I heavy chains. Also participates in the degradation process of misfolded cytomegalovirus US2 protein.
Cellular Location: Endoplasmic reticulum membrane; Multi- pass membrane protein. Tissue Location: Ubiquitous. Blood, Brain, Embryonic Tissue, Kidney, Lymph, Lymph Node, Mammary Gland, Pancreas, Prostate, Vascular tissues are correlated with this protein. DERL1 also interacts with the following gene(s): AMFR, APOB, CFTR, SEC61A1, SEL1L, SVIP, SYVN1, VCP, VIMP. The following patways have been known to be associated with this gene. Brain Diseases, Cardiovascular Diseases, Fibrosis, Genital Diseases, Male, Inflammation, Liver Neoplasms, Lung Diseases, Neoplasms, Experimental, Nervous System Diseases, Prostatic Diseases are some of the diseases may be linked to DERL1 Antibody (C-term) Blocking Peptide.