|The DBP dbp (Catalog #MBS9229885) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The DBP dbp product has the following accession number(s) (GI #1706312) (NCBI Accession #Q10586.1) (Uniprot Accession #Q10586). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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This transcriptional activator recognizes and binds to the sequence 5\'-RTTAYGTAAY-3\' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
Cellular Location: Nucleus. Tissue Location: Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity. Adipose Tissue, Blood, Bone, Brain, Connective Tissue, Kidney, Lung, Muscle, Skin, Testis tissues are correlated with this protein. Atherosclerosis, Cardiomegaly, Cardiovascular Diseases, Edema, Heart Diseases, Hypertension, Hypertrophy, Inflammation, Kidney Diseases, Weight Loss are some of the diseases may be linked to DBP Blocking Peptide (C-term). The following patways have been known to be associated with this gene. DBP also interacts with the following gene(s): ARNTL, CEBPA, CLOCK, HLF, NPAS2, PDXK.