|The Cytochrome P450 2C10 cDNA Probe, BioGenomics n/a (Catalog #MBS651964) is a cDNA and is intended for research purposes only. The product is available for immediate purchase.
Suitable for use for synthesis, by standard random priming or nick translation techniques, of radiolabeled probes for investigations of P450 2C10 gene expression., Optimum dilutions to be determined by researcher. Researchers should empirically determine the suitability of the Cytochrome P450 2C10 cDNA Probe, BioGenomics n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Phase 1 drug metabolism is catalyzed by two groups of monooxygenases, the cytochrome P450s (CYPs) and the flavin monooxygenases (FMOs). Both CYPs and FMOs are localized in the endoplasmic reticulum. Collectively, these enzymes catalyze the oxidation of a very broad range of substrates. Both classes are dependent on NADPH as a source of electrons, but the two classes exhibit significant differences in mechanism and substrate specificity.