|The CYP8B1 cyp8b1 (Catalog #MBS9227849) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The CYP8B1 cyp8b1 product has the following accession number(s) (GI #308153428) (NCBI Accession #Q9UNU6.2) (Uniprot Accession #Q9UNU6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids.
Cellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein. Tissue Location: Liver. The following patways have been known to be associated with this gene. Brain, Kidney, Liver tissues are correlated with this protein. Carcinoma, Hepatocellular, Cholestasis, Drug-Induced Liver Injury, Drug-Related Side Effects and Adverse Reactions, Dyslipidemias, Fatty Liver, Inflammation, Liver Diseases, Liver Neoplasms, Necrosis are some of the diseases may be linked to CYP8B1 Antibody (C-term) Blocking Peptide.