Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Blog  rightarrow CTCF blocking peptide  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • anti-CD15 antibody blog
 • YWHAE elisa kit blog
 • PTH elisa kit blog
 • METTL3 sirna blog
 • Pax6 blocking peptide blog
 • IgG1 secondary antibody blog
 • ZDHHC14 sirna blog
 • EGFR recombinant protein blog
 • anti-FLAG-tag antibody blog
 • PAGE4 sirna blog
 • POLD3 sirna blog
 • PCGF2 blocking peptide blog
 • anti-INS antibody blog
 • TATDN1 shrna blog
 • anti-SLC12A7 antibody blog
 • TCP10 sirna blog
 • hsa-miR-6732-5p mirna blog
 • GLDH enzyme blog
 • MED16 blocking peptide blog
 • GCNT3 sirna blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • CD27 Antibody
 • 14-3-3 zeta Antibody
 • MPG Peptide
 • Carboxypeptidase B (CPB1) Enzyme
 • Ribonuclease A3 (RNASE3) ELISA Kit
 • Cationic trypsin Recombinant Protein
 • S100A8 Recombinant Protein
 • alpha-beta hydrolase domain-containing protein 5 (ABHD5) ELISA Kit
 • HCLS1-associated protein X-1 (HAX1) Recombinant Protein
 • A Disintegrin and Metalloprotease 2 (ADAM2) ELISA Kit
 • ABCC8 siRNA
 • Prostaglandin E2, PG-E2 ELISA Kit
 downarrow more ...

CTCF blocking peptide product blog

Posted on 2017-03-03 23:41:12 by mybiosource_staff
Share it on ...     
Tags: CTCF; Blocking Peptide; CTCF blocking peptide;
The CTCF ctcf (Catalog #MBS9230109) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.

The CTCF ctcf product has the following accession number(s) (GI #1706179) (NCBI Accession #P49711.1) (Uniprot Accession #P49711). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, binding within the H19 imprinting control region (ICR) mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Plays a critical role in gene silencing over considerable distances in the genome. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation and maintaining methylation-free zones. Inversely, binding to target sites is prevented by CpG methylation. Plays an important role in chromatin remodeling. Can dimerize when it is bound to different DNA sequences, mediating long-range chromatin looping. Mediates interchromosomal association between IGF2/H19 and WSB1/NF1 and may direct distant DNA segments to a common transcription factory. Causes local loss of histone acetylation and gain of histone methylation in the beta-globin locus, without affecting transcription. When bound to chromatin, it provides an anchor point for nucleosomes positioning. Seems to be essential for homologous X-chromosome pairing. May participate with Tsix in establishing a regulatable epigenetic switch for X chromosome inactivation. May play a role in preventing the propagation of stable methylation at the escape genes from X- inactivation. Involved in sister chromatid cohesion. Associates with both centromeres and chromosomal arms during metaphase and required for cohesin localization to CTCF sites. Regulates asynchronous replication of IGF2/H19.

CTCF ctcf

Cellular Location: Nucleus, nucleoplasm. Chromosome. Chromosome, centromere. Note: May translocate to the nucleolus upon cell differentiation. Associates with both centromeres and chromosomal arms during metaphase. Associates with the H19 ICR in mitotic chromosomes. May be preferentially excluded from heterochromatin during interphase. Tissue Location: Ubiquitous. Absent in primary spermatocytes. Abnormalities, Multiple, Adenocarcinoma, Carcinoma, Carcinoma, Hepatocellular, Cell Transformation, Neoplastic, Fibrosis, Infertility, Male, Kidney Diseases, Lung Neoplasms, Neoplasms, Experimental are some of the diseases may be linked to CTCF Blocking Peptide (Center).
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions