|The CSF2 csf2 (Catalog #MBS197007) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The CSF2 csf2 product has the following accession number(s) (GI #27437030) (NCBI Accession #NP_000749.2) (Uniprot Accession #P04141). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
AMINO ACID SEQUENCEThe first five N-terminal amino acids are Ala-Pro-Al a-Arg-Ser. N-terminal methionine is removed enzymatica lly.
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Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF) are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Biological Activity: E050 by dose-dependent stimulation of proliferation of human TF-1 cells (human erythroleukemic indicator cell line) is <0.1ng/ml which corresponds to a Specific Activity of 11,100,000 IU/mg. Bacterial Infections, Bone Marrow Diseases, Hematologic Diseases, Immune System Diseases, Inflammation, Leukemia, Lung Diseases, Necrosis, Neoplasms, Respiratory Tract Diseases are some of the diseases may be linked to Recombinant Human Granulocyte Macrophage Colony Stimulating Factor (rHuGM-CSF). The following patways have been known to be associated with this gene. CSF2 also interacts with the following gene(s): CSF2RA, CSF2RB, IL3RA, KITLG, SDC2. Blood, Bone, Lung tissues are correlated with this protein.