CLIC5 blocking peptide product blog
Tags: Blocking Peptide; CLIC5; CLIC5 blocking peptide;
The CLIC5 clic5 (Catalog #MBS9227021) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The CLIC5 clic5 product has the following accession number(s) (GI #215274174) (NCBI Accession #Q9NZA1.3) (Uniprot Accession #Q9NZA1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Required for normal hearing (PubMed:24781754). It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture (PubMed:15184393, PubMed:18028448, PubMed:20335315).
Cellular Location: Isoform 1: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Membrane; Single-pass membrane protein. Note: Associates with the cortical actin cytoskeleton. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity). Tissue Location: Widely expressed in both fetal and adult human tissues (PubMed:24781754). Isoform 1 is expressed in renal glomeruli endothelial cells and podocytes (at protein level). Brain Diseases, Carcinoma, Hepatocellular, Congenital Abnormalities, Fibrosis, Kidney Diseases, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Proteinuria are some of the diseases may be linked to CLIC5 Antibody Blocking Peptide. Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Placenta, Stomach tissues are correlated with this protein.