|The CHST10 chst10 (Catalog #MBS9222628) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The CHST10 chst10 product has the following accession number(s) (GI #61211695) (NCBI Accession #O43529.1) (Uniprot Accession #O43529). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
Cellular Location: Golgi apparatus membrane; Single-pass type II membrane protein. Tissue Location: In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver. In adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues In brain, it is expressed at higher level in the frontal lobe. Cell Transformation, Neoplastic, Inflammation, Memory Disorders, Necrosis, Neoplasm Metastasis are some of the diseases may be linked to CHST10 Antibody (C-term) Blocking Peptide. The following patways have been known to be associated with this gene. Blood, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Lymph Node, Nerve, Ovary tissues are correlated with this protein.