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CHIR-99021 inhibitor product blog

Posted on 2015-11-26 12:25:47 by mybiosource_staff
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Tags: Inhibitor; CHIR-99021; CHIR-99021 inhibitor;
The CHIR-99021 n/a (Catalog #MBS515063) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given inhibitor. We\'ve tested the CHIR-99021 with the following immunoassay(s):
Molecular Structure
Molecular Structure CHIR-99021.

GSK3beta inhibitor

Scientific Background: Potent and selective inhibitor of glycogen synthase kinase-3beta(GSK3beta, IC50 = 5 nM) and GSK3alpha (IC50 = 10 nM) (1). Induces osteoblastogenesis, increases mineralization and inhibits adipogenesis in ST2 cells (2). Promotes replication and survival of pancreatic beta cells (3). Enhances differentiation and reduces proliferation of adult human olfactory epithelium neural precursors (4). Cell permeable and active in vivo.

CAS Number: 252917-06-9
Molecular Formula: C22H18Cl2N8. Activity: EGFR inhibitor
Solubilization: May be dissolved in DMSO (25 mg/ml, warm).
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