Celastrol small molecule product blog
Tags: Celastrol; Small Molecule; Celastrol small molecule;
The Celastrol n/a (Catalog #MBS808038) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given small molecule. We\'ve tested the Celastrol with the following immunoassay(s):
Chemical Structure (Chemical structure of Celastrol (SIH-333), a Proteasome inhibitor. CAS #: 34157-83-0. Molecular Formula: C29H38O4. Molecular Weight: 450.6 g/mol.)
Displays potent antioxidant and anti-inflammatory activity. Inhibits NF?B (IC50=270 nM). It induces heat shock response and cytoprotection in various cells. It inhibits 20S proteasome chymotrypsin activity (IC50=2.5 ?M). Cell permeable.
Solubility: Soluble in 45 mg/ml DMSO, 30 mg/ml Ethanol
CAS Number: 34157-83-0
Molecular Formula: C29H38O4
SMILES: CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O
InChI: 1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
InChI Key: KQJSQWZMSAGSHN-JJWQIEBTSA-N
PubChem CID: 122724.