|The CDKN2B cdkn2b (Catalog #MBS9219282) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The CDKN2B cdkn2b product has the following accession number(s) (GI #1168869) (NCBI Accession #P42772.1) (Uniprot Accession #P42772). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Cellular Location: Cytoplasm. Note: Also found in the nucleus. Tissue Location: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines. CDKN2B also interacts with the following gene(s): CCND1, CDK4, CDK6, CDKN1A, CDKN1B, MYC, SMAD2, SMAD3, SMAD4, ZBTB17. The following patways have been known to be associated with this gene. Bladder, Brain, Embryonic Tissue, Liver, Lung, Muscle, Pancreas, Prostate, Skin, Stomach tissues are correlated with this protein. Adenocarcinoma, Brain Diseases, Carcinoma, Squamous Cell, Cardiovascular Diseases, Cell Transformation, Neoplastic, Chromosome Aberrations, Coronary Artery Disease, Glioma, Lymphoma, Myelodysplastic Syndromes are some of the diseases may be linked to CDKN2B Antibody (C-term) Blocking peptide.