Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Blog  rightarrow CDH2 peptide  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • PTPN6 sirna blog
 • MARVELD2 blocking peptide blog
 • GSDMC recombinant protein blog
 • anti-Aqp8 antibody blog
 • anti-CD54 antibody blog
 • HIV-1 gp120 recombinant protein blog
 • STAT1 blocking peptide blog
 • anti-ABCG1 antibody blog
 • Tenofovir inhibitor blog
 • anti-Feline Leukemia Virus (FeLV) gp70 antibody blog
 • MAPK7 blocking peptide blog
 • C2orf83 blocking peptide blog
 • F recombinant protein blog
 • cgkA recombinant protein blog
 • TF elisa kit blog
 • IFRD1 sirna blog
 • Boc-Gln-ONp amino acid blog
 • anti-ANG1 antibody blog
 • anti-CAV1 antibody blog
 • NMB recombinant protein blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • phospholipase B domain containing 2 (PLBD2) ELISA Kit
 • Matrix Metalloproteinase 13 (MMP-13) ELISA Kit
 • Myoglobin (Antigen grade) (MB) Protein
 • CHLORAMPHENICOL Antibody
 • Goat anti Canine IgE Secondary Antibody
 • Gamma-aminobutyric acid receptor subunit gamma-2 (Gabrg2) Recombinant Protein
 • Alpha-amylase 2B (AMY2B) ELISA Kit
 • Lysosomal-trafficking regulator (Lyst) Recombinant Protein
 • Mesothelin (MSLN) Recombinant Protein
 • Defensin-5 (DEFA5) ELISA Kit
 • RAB3C, member RAS oncogene family ELISA Kit
 • Glycerol-3-Phosphate Dehydrogenase 1, Soluble (GPD1) ELISA Kit
 • KMT4 - Dot1L Antibody
 • RuBisCO Antibody
 downarrow more ...
separator

CDH2 peptide product blog

separator
Posted on 2013-11-27 14:39:50 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Peptide; CDH2; N-Cadherin (a.a. 811-824) Peptide; CDH2 peptide;
separator
The CDH2 cdh2 (Catalog #MBS474012) is a Peptide and is intended for research purposes only. The product is available for immediate purchase.
ELISA: 50 ng/well
Western Blot: 1 mg/ml. Researchers should empirically determine the suitability of the CDH2 cdh2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The CDH2 cdh2 product has the following accession number(s) (GI #253483) (Uniprot Accession #P19022). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Peptide Sequence: Unphosphor ylated N-cadherin (a.a. 811-824) synthetic peptide generated from human N-cadherin. This sequence is conserved in rat and mouse Ncadherin, and has three amino acid difference s from the conserved region in R-cadherin.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Cadherins are transmembrane glycoproteins vital in calcium-dependent cell-cell adhesion during tissue differentiation. Cadherins cluster to form foci of homophilic binding units. A key determinant to the strength of the cadherin-mediated adhesion may be by the juxtamembrane region in cadherins. This region induces clustering and also binds to the protein p120 catenin. The cytoplasmic region is highly conserved in sequence and has been shown experimentally to regulate the cell-cell binding function of the extracellular domain of E-cadherin, possibly through interaction with the cytoskeleton. Many cadherins are regulated by phosphorylation, including N-cadherin and E-cadherin. N-cadherin is phosphorylated by c-Src at Tyr-820, Tyr-853, Tyr-860, Tyr-884, and Tyr-886. Phosphorylation of Tyr-860 can disrupt cadherin binding to beta-catenin. Since many of these tyrosine sites are conserved in the cadherin family, phosphorylation of these sites may be critical for cadherin function.

CDH2 cdh2

The following patways have been known to be associated with this gene. Brain tissues are correlated with this protein. CDH2 also interacts with the following gene(s): ARVCF, CDH11, CDH4, CTNNA1, CTNNB1, JUP. Adenocarcinoma, Carcinoma, Cardiovascular Diseases, Endocrine Gland Neoplasms, Female Urogenital Diseases, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Neuroectodermal Tumors, Skin Diseases are some of the diseases may be linked to N-Cadherin (a.a. 811-824) Peptide.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions