C1QB native protein product blog
Tags: Native Protein; Complement C1q; C1QB; C1QB native protein;
The C1QB c1qb (Catalog #MBS537423) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase.The C1QB c1qb product has the following accession number(s) (GI #87298828) (NCBI Accession #NP_000482.3) (Uniprot Accession #P02746). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Complement C1q are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Source Note: Human serum/plasma
Protein Type: Native
Biological Significance: C1q is part of the C1 complex and this complex is the first complement component in the cascade referred to as the classical pathway of complement. C1 is actually a non-covalent assembly of three different proteins (C1q, C1r, and C1s) bound together in a calcium-dependent complex. C1q has six extended arms with domains at the end of each arm that bind to the Fc domains of immunoglobulins.
Bioactivity: >1,000,000 C1H50 units/mg. Biohazard Information: Donor samples were tested and found to be negative for HBsAg, HTLV-I/II, STS, and for antibodies to HCV, HIV-1 and HIV-II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product. Bone, Brain, Connective Tissue, Eye, Kidney, Liver, Lung, Mouth, Spleen, Vascular tissues are correlated with this protein. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Kidney Diseases, Learning Disorders, Liver Diseases, Memory Disorders, Necrosis, Nervous System Diseases, Poisoning are some of the diseases may be linked to Complement C1q protein. The following patways have been known to be associated with this gene. C1QB also interacts with the following gene(s): C1QA, C1QC, C1R, C1S, C4B, CRP, CSTB, SERPING1.