Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Blog  rightarrow c-erbB proto-oncogene peptide  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • VDAC1 blocking peptide blog
 • ZNF609 shrna blog
 • anti-F9 antibody blog
 • EPDR1 sirna blog
 • Jatrorrhizine inhibitor blog
 • NUP93 sirna blog
 • Pv MSP recombinant protein blog
 • MCPT4 shrna blog
 • MEA1 sirna blog
 • GZMB blocking peptide blog
 • SYNRG sirna blog
 • Tissue Array, BioAssay Lung squamous cell carcinoma, grade I ~ III tissue array blog
 • AMIGO1 blocking peptide blog
 • anti-Procalcitonin/Calcitonin antibody blog
 • anti-GAD67 antibody blog
 • TCR alpha beta (V beta 2) secondary antibody blog
 • anti-Tri-methyl Lysine antibody blog
 • Psalmotoxin 1 biologically active peptide blog
 • CNKSR3 shrna blog
 • CASPASE-3/7 kits blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • fibroblast activation protein, alpha (FAP) ELISA Kit
 • Netrin G1 (NTNG1) Antibody
 • vitamin K epoxide reductase complex, subunit 1-like 1 (VKORC... ELISA Kit
 • Transthyretin (TTR) Recombinant Protein
 • Collagen and calcium-binding EGF domain-containing protein 1... Recombinant Protein
 • COX7A1 Antibody
 • Eosinophil Peroxidase (EPX) ELISA Kit
 • Disintegrin and metalloproteinase domain-containing protein ... ELISA Kit
 • Histone H3 Antibody
 • Ghrelin (GHRL) Antibody
 • Activation-induced cytidine deaminase (AICDA) ELISA Kit
 • Actin-related protein 2-3 complex subunit 2 (Arpc2) Recombinant Protein
 • Asymmetric dimethylarginine (ADMA) ELISA Kit
 • CD8a (Ly 2) (CD8a (Ly 2)) Antibody
 downarrow more ...
separator

c-erbB proto-oncogene peptide product blog

separator
Posted on 2015-04-29 00:15:30 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Peptide; phospho-EGFR (Ser-1142) Peptide; c-erbB proto-oncogene peptide; c-erbB proto-oncogene;
separator
The c-erbB proto-oncogene c-erbb proto-oncogene (Catalog #MBS474032) is a Peptide and is intended for research purposes only. The product is available for immediate purchase.
ELISA: 50 ng/well
Immunocytochemistry: 1:500
Western Blot: 1:1,000. Researchers should empirically determine the suitability of the c-erbB proto-oncogene c-erbb proto-oncogene for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The c-erbB proto-oncogene c-erbb proto-oncogene product has the following accession number(s) (GI #8815559) (NCBI Accession #AAB19486.2) (Uniprot Accession #Q9P2Z9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Peptide Sequence: Phospho-EG FR (Ser-1142) synthetic peptide correspond ing to amino acid residues surroundin g serine 1142 of human EGFR (ErbB-1). This human EGFR sequence has high homology with rat and mouse EGFR, and is not conserved in other ErbB family members.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein with an extracellular ligand-binding domain and a cytoplasmic domain with intrinsic tyrosine kinase activity. The cytoplasmic domain has a C-terminal region with multiple autophosphorylation sites (Tyr-992, 1068, 1086, 1148, and 1173). These sites are important for downstream signaling and rapid internalization. In addition, EGFR activation leads to c-Src mediated phosphorylation of Tyr-845 and Tyr-1101. The former site is required for mitogenic responses to EGFR activation, while the latter may be an SH2 binding site. Phosphorylation of EGFR on serine and threonine residues is thought to represent a mechanism for regulation of receptor kinase activity and internalization. These sites include a PKC site (Thr-654), CAMKII sites (Ser-1046, 1047, 1057, and 1142), and constitutively phosphorylated sites (Ser-967 and Ser-1002). Thus, the regulation of EGFR activity involves a complex series of phosphorylation events at multiple sites throughout the intracellular portion of the receptor.

c-erbB proto-oncogene c-erbb proto-oncogene

The following patways have been known to be associated with this gene. c-erbB proto-oncogene also interacts with the following gene(s): FLNA.
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions
126 - Incorrect key file for table './mbsds_xtra/sessions.MYI'; try to repair it

insert into sessions values ('da4a904e267dfbb2e1dd4a26e18576a0', '1537310883', 'cart|O:12:\"shoppingCart\":4:{s:8:\"contents\";a:0:{}s:5:\"total\";i:0;s:6:\"weight\";i:0;s:12:\"content_type\";b:0;}wishlist|O:14:\"wishlist_class\":4:{s:8:\"contents\";a:0:{}s:5:\"total\";i:0;s:6:\"weight\";i:0;s:12:\"content_type\";b:0;}currency|s:3:\"USD\";navigation|O:17:\"navigationHistory\":2:{s:4:\"path\";a:1:{i:0;a:4:{s:4:\"page\";s:8:\"blog.php\";s:4:\"mode\";s:6:\"NONSSL\";s:3:\"get\";a:2:{s:4:\"subd\";s:4:\"blog\";s:4:\"code\";s:36:\"c-erbb-proto-oncogene-peptide_474032\";}s:4:\"post\";a:0:{}}}s:8:\"snapshot\";a:0:{}}')

[TEP STOP]