|The BST2 bst2 (Catalog #MBS542577) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s BST2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western Blot: 1:500-1:1,000. Researchers should empirically determine the suitability of the BST2 bst2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BST2 bst2 product has the following accession number(s) (GI #62897809) (NCBI Accession #BAD96844) (Uniprot Accession #Q10589). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Western Blot Positive Control Bonemarrow stromal antigen 2
IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.
Immunogen: Purified Protein
Expression: Liver, lung, heart and placenta. Lower levels in pancreas, kidney, skeletal msucle and brain. Overexpressed in multiple myeloma cells. B-cells, T-cells, monocytes, NK cells and dendritic cells. Induced by type I interforns. Down regulated by viral antagonistic factors. Molecular Function: Antiviral defense; B-cell activation; Immunity; Innate immunity
Structure: Parallel homodimer; disulfide linked. Cytoplasmic domain interacts with ARHGAP44 and MMP14.
Subcellular Location: Gogli apparatus, trans-golgi network; Cell membrane, Single-pass type II membrane protein. Lipid anchor, GPI anchor; Late endosome; Membrane raft; Cytoplasm; Apical cell membrane. BST2 also interacts with the following gene(s): APOBEC3G, ARHGAP44, IRF7, TRIM5. Blood, Bone, Bone Marrow, Brain, Kidney, Liver, Lung, Skin, Spleen, Uterus tissues are correlated with this protein. The following patways have been known to be associated with this gene. Breast Neoplasms, Inflammation, Kidney Diseases, Liver Diseases, Liver Neoplasms, Lung Neoplasms, Multiple Myeloma, Neoplasms, Experimental, Nervous System Diseases, Skin Diseases are some of the diseases may be linked to BST2 Positive Control.