|The bIGF1 igf1 (Catalog #MBS142303) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase.
The bIGF1 igf1 product has the following accession number(s) (GI #126722801) (NCBI Accession #NP_001075495.1) (Uniprot Accession #Q95222). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
MTAGPETLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKP.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including Insulin Like Growth Factor-1 are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Solubility: It is recommended to reconstitute the lyophilized rbIGF-I in sterile 0.4% NaHCO3 adjusted, not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity: IGF-I is biologically active when compared to human IGF-1. The ED50, calculated by the dose -dependent proliferation of human MCF/7 cells is 5 to 25ng/ml in the cell culture mixture dependent on culture conditions. Its activity consists of 30-40 % compared to human IGF-1. The following patways have been known to be associated with this gene. Acromegaly, Adenoma, Breast Neoplasms, Female Urogenital Diseases, Hypertension, Inflammation, Liver Diseases, Necrosis, Pituitary Neoplasms, Prostatic Neoplasms are some of the diseases may be linked to Recombinant Rabbit Insulin Like Growth Factor-1.