BID blocking peptide product blog
Tags: BID; Blocking Peptide; BID blocking peptide; Bid (BH3 Domain Specific);
The BID bid (Catalog #MBS9219642) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The BID bid product has the following accession number(s) (GI #2493285) (NCBI Accession #P55957.1) (Uniprot Accession #P55957). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Cellular Location: Cytoplasm. Mitochondrion membrane. Note: When uncleaved, it is predominantly cytoplasmic. BH3-interacting domain death agonist p13: Mitochondrion membrane. Note: Associated with the mitochondrial membrane. Isoform 3: Cytoplasm. Tissue Location: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level) Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level). Blood, Bone, Brain, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. BID also interacts with the following gene(s): BAK1, BAX, BCL2L1, CASP10, CASP8, FADD, FASLG, MCL1. Cardiovascular Diseases, Diarrhea, Heart Diseases, Hypertension, Inflammation, Liver Diseases, Lung Diseases, Necrosis, Nervous System Diseases, Pain are some of the diseases may be linked to Bid Antibody (BH3 Domain Specific) Blocking peptide.