BAFF recombinant protein product blog
Tags: Recombinant Protein; BAFF; BAFF recombinant protein;
The BAFF tnfrsf13c (Catalog #MBS539429) is an Active Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s BAFF can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the BAFF tnfrsf13c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The BAFF tnfrsf13c product has the following accession number(s) (GI #15208475) (NCBI Accession #AAK91826.1) (Uniprot Accession #Q5H8V1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:
Region of BAFF Receptor protein correspond ing to amino acids MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Our knowledge of the role of proteins in cellular processes is continually evolving. Most proteins, including BAFF are typically involved in one or more signaling pathways or biological processes. Professionally manufactured recombinant proteins are increasingly becoming essential and commonplace tools for elucidating new knowledge about the role of proteins in both health and disease.
Protein Type: Recombinant
Biological Significance: BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation.
Bioactivity: Determined by its ability to bl degree Ck BAFF induced mouse splen degree Cyte survival. The expected ED50 for this effect is 2.0-4.0 ug/ml in the presence of 1.0ug/ml of human soluble BAFF.
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug). Expression System: E Coli. BAFF also interacts with the following gene(s): BCR, BTK, REL, RELA, TNFRSF13B, TNFRSF17, TNFSF13B, TRAF2, TRAF3. Atherosclerosis, Common Variable Immunodeficiency, Demyelinating Diseases, Hyperplasia, Hypertrophy, Immune System Diseases, Inflammation, Kidney Diseases, Necrosis, Skin Diseases are some of the diseases may be linked to BAFF Receptor protein. Lymph Node tissues are correlated with this protein. The following patways have been known to be associated with this gene.