BAAT blocking peptide product blog
Tags: Blocking Peptide; BAAT; BAAT blocking peptide;
The BAAT baat (Catalog #MBS9230627) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The BAAT baat product has the following accession number(s) (GI #74739811) (NCBI Accession #Q14032.1) (Uniprot Accession #Q14032). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Involved in bile acid metabolism. In liver hepatocytes catalyzes the second step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi. The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl-CoA thioester, either in peroxisomes (primary bile acids deriving from the cholesterol pathway), or cytoplasmic at the endoplasmic reticulum (secondary bile acids). May catalyze the conjugation of primary or secondary bile acids, or both. The conjugation increases the detergent properties of bile acids in the intestine, which facilitates lipid and fat-soluble vitamin absorption. In turn, bile acids are deconjugated by bacteria in the intestine and are recycled back to the liver for reconjugation (secondary bile acids). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs.
Cellular Location: Cytoplasm. Tissue Location: Expressed in liver, gallbladder mucosa and pancreas. Heart, Liver, Lung, Muscle, Skin tissues are correlated with this protein. The following patways have been known to be associated with this gene. Atrophy, Brain Diseases, Cholestasis, Cholestasis, Intrahepatic, Drug-Related Side Effects and Adverse Reactions, Fatty Liver, Fibrosis, Inflammation, Liver Cirrhosis, Liver Diseases are some of the diseases may be linked to BAAT Blocking Peptide (N-Term).