ATXN1L blocking peptide product blog
Tags: Blocking Peptide; ATXN1L; ATXN1L blocking peptide;
The ATXN1L atxn1l (Catalog #MBS9223743) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ATXN1L atxn1l product has the following accession number(s) (GI #206557834) (NCBI Accession #P0C7T5.1) (Uniprot Accession #P0C7T5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity).
Cellular Location: Nucleus. Cell projection, dendrite. Note: Forms nuclear foci. Colocalizes with NCOR2 and HDAC3. Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells. Tissue Location: Expressed in cerebellum and cerebral cortex. Blood, Brain, Embryonic Tissue, Eye, Lung tissues are correlated with this protein. Brain Diseases, Nerve Degeneration, Spinocerebellar Ataxias are some of the diseases may be linked to ATXN1L Antibody (Center) Blocking Peptide.