AT-406 inhibitor product blog
Tags: Inhibitor; AT-406; AT-406 inhibitor;
The AT-406 n/a (Catalog #MBS578344) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase.To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins (IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
CAS: 1071992-57-8
Smiles: Cl.CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C. Formula: C32H43N5O4.