ASCL1 blocking peptide product blog
Tags: Blocking Peptide; ASCL1; ASCL1 blocking peptide; ASCL1 (Achaete-scute homolog 1);
The ASCL1 ascl1 (Catalog #MBS9228874) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.The ASCL1 ascl1 product has the following accession number(s) (GI #55743094) (NCBI Accession #NP_004307) (Uniprot Accession #P50553). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5\'-CANNTG- 3\'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
Cellular Location: Nucleus. ASCL1 also interacts with the following gene(s): HES1, HES6, MEF2A, NEUROG1, NEUROG2, NOTCH1, PHOX2A, SHH, TCF3, TCF4. The following patways have been known to be associated with this gene. Adenocarcinoma, Cell Transformation, Neoplastic, Death, Disease Models, Animal, Hyperplasia, Lung Diseases, Lung Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Small Cell Lung Carcinoma are some of the diseases may be linked to ASCL1 (Achaete-scute homolog 1) Blocking Peptide (C-term D220). Brain, Embryonic Tissue, Eye, Kidney, Lung, Lymph Node, Nerve, Pancreas, Thyroid, Uncharacterized Tissue tissues are correlated with this protein.