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AQP4 positive control product blog

Posted on 2017-03-03 20:33:22 by mybiosource_staff
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Tags: Aquaporin 4; AQP4; Positive Control; AQP4 positive control;
The AQP4 aqp4 (Catalog #MBS542537) is a Positive Control and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s Aquaporin 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western Blot: 1:500. Researchers should empirically determine the suitability of the AQP4 aqp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The AQP4 aqp4 product has the following accession number(s) (GI #4502181) (NCBI Accession #NP_001641) (Uniprot Accession #P55087). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given positive control. We\'ve tested the Aquaporin 4 Antibody Positive Control with the following immunoassay(s):
Western Blot (WB)
Western Blot (WB) AQP4.

Forms water specific channel. Osmoreceptor which regulates water balance and mediates water flow within CNS.

Immunogen: Purified Protein
Expression: Abundant in mature brain but only weakly detectable in eye, kidney, intestine, and lung. Molecular Function: Transport
Structure: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Subcellular Location: Membrane; Multi-pass protein. Brain, Embryonic Tissue, Eye, Intestine, Kidney, Lung, Muscle, Nerve, Spinal Cord, Vascular tissues are correlated with this protein. AQP4 also interacts with the following gene(s): AQP2, AVP, HMOX1, KCNJ10, TRPV4. Brain Diseases, Cardiovascular Diseases, Disease Models, Animal, Edema, Hypertension, Inflammation, Kidney Diseases, Necrosis, Nervous System Diseases, Neuromyelitis Optica are some of the diseases may be linked to Aquaporin 4 Antibody Positive Control.
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