Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Blog  rightarrow Apicidin antibiotic  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
separator
 • CHMP4A sirna blog
 • gp120 recombinant protein blog
 • SEC22C sirna blog
 • LRP2BP elisa kit blog
 • anti-AIF1 antibody blog
 • ASM elisa kit blog
 • Influenza A, Caledonia 20/99 IVR 116 infectious disease blog
 • anti-hCG HOLO antibody blog
 • PLS1 sirna blog
 • GRN elisa kit blog
 • CARKD sirna blog
 • PON1 sirna blog
 • ATG5 peptide blog
 • anti-HTR7 antibody blog
 • GSDMC sirna blog
 • SMU1 sirna blog
 • SDC1 blocking peptide blog
 • EHBP1 sirna blog
 • UPP2 sirna blog
 • Amaranthus caudatus lectin blog
separator
Blog Categories separator
separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
separator
Our Best Sellers moreseparator
separator
 • ADRA1B Antibody
 • A Disintegrin and Metalloprotease 8 (ADAM8) ELISA Kit
 • 3-ketodihydrosphingosine reductase (KDSR) ELISA Kit
 • Prominin 1 (PROM1) Antibody
 • 26S protease regulatory subunit 6B (PSMC4) ELISA Kit
 • Annexin A10 - Annexin 14 (ANXA10) Peptide
 • Angiopoietin 1 (ANG1) ELISA Kit
 • alpha-Melanocyte Stimulating Hormone (alpha-MSH) ELISA Kit
 • Intercellular Adhesion Molecule 1 (ICAM-1) ELISA Kit
 • Cyclin-dependent kinase 2 (Cdk2) ELISA Kit
 • Albumin, Bovine Serum, IgG & Protease Free, 30% Protein
 • Glycogen Synthase Kinase 3 alpha, beta (GSK3A) Antibody
 • 1-acyl-sn-glycerol-3-phosph ate acyltransferase beta (AGPAT2) ELISA Kit
 • Dorsal-related immunity factor Dif (Dif), partial Recombinant Protein
 downarrow more ...
separator

Apicidin antibiotic product blog

separator
Posted on 2015-12-29 08:27:58 by mybiosource_staff
Share it on ...     
separator
separator
Tags: Antibiotic; Apicidin; Apicidin antibiotic;
separator
The Apicidin n/a (Catalog #MBS651532) is an Antibiotic produced from Fusarium sp. and is intended for research purposes only. The product is available for immediate purchase.
Suitable for use as a histone deacetylase inhibitor. Other applications have not been tested. Researchers should empirically determine the suitability of the Apicidin n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Apicidin n/a product has the following accession number(s) (GI #270269268) (NCBI Accession #ACZ66258.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin.

Apicidin n/a

CAS Number: 183506-66-3
Molecular Formula: C34H49N5O6. Solubility: Reconstitute in DMSO or ethanol (~50mg/ml).
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions