Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Blog  rightarrow Apicidin antibiotic  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • IgM positive control blog
 • anti-GPR32 antibody blog
 • SSX1 blocking peptide blog
 • NXPH1 blocking peptide blog
 • GPR132 sirna blog
 • anti-SST antibody blog
 • 14-3-3 eta recombinant protein blog
 • Rabbit F(ab')2 Anti-Sheep IgG (H+L) secondary antibody blog
 • Streptavidin poly-hrp blog
 • IL10 elisa kit blog
 • PSMD4 recombinant protein blog
 • anti-APBA1 antibody blog
 • CNTRL sirna blog
 • Skin slide blog
 • anti-Staphylococcus Aureus enterotoxin type I antibody blog
 • anti-IgG antibody blog
 • MPO protein blog
 • anti-RSK1 antibody blog
 • IL1RL2 blocking peptide blog
 • anti-PKC delta antibody blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • AVPR2 Antibody
 • PABPC5 Antibody
 • EPHA1 Antibody
 • Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2) ELISA Kit
 • Phosphatidylinositol Antibody IgM (PI AB-IgM) ELISA Kit
 • Gremlin 1 (GREM1) ELISA Kit
 • Growth Hormone Antibody (GH) ELISA Kit
 • Cluster of Differentiation 74 (CD74) ELISA Kit
 • Ornithine Carbamoyl Transferase (OCT) ELISA Kit
 • Stromal Cell Derived Factor 4 (SDF4) ELISA Kit
 • Inhibin Beta A (INHbetaA) ELISA Kit
 • Steroidogenic Factor 1 (SF1) ELISA Kit
 • Cluster of Differentiation 19 (CD19) ELISA Kit
 • Resistin ELISA Kit
 downarrow more ...

Apicidin antibiotic product blog

Posted on 2015-12-29 08:27:58 by mybiosource_staff
Share it on ...     
Tags: Antibiotic; Apicidin; Apicidin antibiotic;
The Apicidin n/a (Catalog #MBS651532) is an Antibiotic produced from Fusarium sp. and is intended for research purposes only. The product is available for immediate purchase.
Suitable for use as a histone deacetylase inhibitor. Other applications have not been tested. Researchers should empirically determine the suitability of the Apicidin n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Apicidin n/a product has the following accession number(s) (GI #270269268) (NCBI Accession #ACZ66258.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin.

Apicidin n/a

CAS Number: 183506-66-3
Molecular Formula: C34H49N5O6. Solubility: Reconstitute in DMSO or ethanol (~50mg/ml).
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions