Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Blog  rightarrow Apicidin antibiotic  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Blogs moreseparator
 • CCL11 elisa kit blog
 • Orexin 2 Receptor Agonist inhibitor blog
 • anti-b-Amyloid antibody blog
 • IL17 recombinant protein blog
 • PMM2 blocking peptide blog
 • anti-NPAS3 antibody blog
 • anti-Hsp27 antibody blog
 • anti-ampC antibody blog
 • CES5A sirna blog
 • FOXP3 peptide blog
 • anti-CANX antibody blog
 • PLEKHB1 sirna blog
 • Mouse Anti-Human IgG4 (gamma 4 chain specific) secondary antibody blog
 • JAK2 sirna blog
 • SIGLEC8 blocking peptide blog
 • Tetracycline inhibitor blog
 • anti-SPHK antibody blog
 • anti-VPRBP antibody blog
 • NCR1 sirna blog
 • ADM peptide blog
Blog Categories separator
 • Assay Kit Blogs
 • Biochemical Blogs
 • cDNA Clone Blogs
 • Monoclonal Antibody Blogs
 • Polyclonal Antibody Blogs
 • Rec/Purified Protein Blogs
 • Popular Product Blogs
Our Best Sellers moreseparator
 • UPF0325 protein yaeH (yaeH) Recombinant Protein
 • PNMA2 Antibody
 • Anti-calsequestrin antibody (AC) ELISA Kit
 • Fibrinopeptide A (FPA) ELISA Kit
 • SHP1 Antibody
 • HABP2 Antibody
 • Protachykinin (Gamma-PPT) Recombinant Protein
 • Antigen peptide transporter 2 (TAP2) ELISA Kit
 • ADAM17 Antibody
 • Uncharacterized RING finger protein C947.10 (SPBC947.10) (ds... Recombinant Protein
 • Avian Influenza Nonstructural Protein 1 (NS1) Blocking Peptide
 • Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) ELISA Kit
 • Tenascin-X (TNXB) Antibody
 • Leukocyte Elastase Inhibitor (LEI) ELISA Kit
 downarrow more ...

Apicidin antibiotic product blog

Posted on 2015-12-29 08:27:58 by mybiosource_staff
Share it on ...     
Tags: Antibiotic; Apicidin; Apicidin antibiotic;
The Apicidin n/a (Catalog #MBS651532) is an Antibiotic produced from Fusarium sp. and is intended for research purposes only. The product is available for immediate purchase.
Suitable for use as a histone deacetylase inhibitor. Other applications have not been tested. Researchers should empirically determine the suitability of the Apicidin n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The Apicidin n/a product has the following accession number(s) (GI #270269268) (NCBI Accession #ACZ66258.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Apicidin is a cyclic peptide antibiotic with broad spectrum antiparasitic and antiprotozoan activity. Apicidin, a histone deacetylase inhibitor, is anti-angiogenic and induces apoptosis. A potent, cell permeable inhibitor of histone deacetylase (IC50 = 700 pM for parasitic histone deacetylase). Inhibits HeLa cell proliferation (IC50 = 50 - 100 nM) and induces the transcriptional activation of p21 (WAF1) in a reversible manner. Also prevents H-ras-induced invasive phenotype of MCF-10A cells possibly by down regulating MMP-2 in a reversible manner. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin.

Apicidin n/a

CAS Number: 183506-66-3
Molecular Formula: C34H49N5O6. Solubility: Reconstitute in DMSO or ethanol (~50mg/ml).
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions