|The APCDD1 (HGNC:15718) apcdd1 (Catalog #MBS9219860) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase.
The APCDD1 (HGNC:15718) apcdd1 product has the following accession number(s) (GI #74728445) (NCBI Accession #Q8J025.1) (Uniprot Accession #Q8J025). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Cellular Location: Cell membrane; Single-pass type I membrane protein. Tissue Location: Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. Abundantly expressed in both the epidermal and dermal compartments of the hair follicle. Present in scalp skin Highly expressed in the hair follicle dermal papilla, the matrix, and the hair shaft (at protein level). Bone, Brain, Embryonic Tissue, Eye, Kidney, Liver, Lung, Mouth, Placenta, Skin tissues are correlated with this protein. Disease Models, Animal, Hypertension, Hypotrichosis simplex, Kidney Diseases, Lung Diseases, Lung Neoplasms are some of the diseases may be linked to APCDD1 Antibody (N-term) Blocking peptide.