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anti-ZSCAN4 antibody product blog

Posted on 2013-09-07 05:25:27 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; ZSCAN4; anti-ZSCAN4 antibody;
The ZSCAN4 zscan4 (Catalog #MBS151547) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZSCAN4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ZSCAN4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
ZSCAN4 antibody can be used for detection of ZSCAN4 by Western blot. Antibody can also be used for immunohistochemistry starting at 5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the ZSCAN4 zscan4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ZSCAN4 zscan4 product has the following accession number(s) (GI #22749365) (NCBI Accession #NP_689890.1) (Uniprot Accession #Q8NAM6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZSCAN4 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ZSCAN4 in mouse lung tissue lysate with ZSCAN4 antibody in (A) the absence and (B) presence of peptide blocking.)
Western Blot (WB) ZSCAN4.

Immunofluorescence (IF) (Immunofluorescence of ZSCAN4 in Rat Lung cells with ZSCAN4 antibody at 20 μg/mL.)
Immunofluorescence (IF) ZSCAN4.

Immunohistochemistry (IHC) (Immunohistochemistry of ZSCAN4 in rat lung tissue with ZSCAN4 antibody at 5 μg/mL.)
Immunohistochemistry (IHC) ZSCAN4.

ZSCAN4 Antibody: Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.

Conjugate: Unconjugated
Immunogen: ZSCAN4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human ZSCAN4.
Buffer: ZSCAN4 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZSCAN4 are readily searchable from our website. Different antibodies against the same target such as ZSCAN4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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