anti-ZBTB7B antibody product blog
Tags: Antibody; Monoclonal Antibody; ZBTB7B; anti-ZBTB7B antibody;
The ZBTB7B zbtb7b (Catalog #MBS850030) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ZBTB7B Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ZBTB7B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA).WB: 1:500-1:2000
IHC: 1:200-1:1000
IF: 1:200-1:1000
ELISA: 1:10000. Researchers should empirically determine the suitability of the ZBTB7B zbtb7b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ZBTB7B zbtb7b product has the following accession number(s) (GI #356995909) (NCBI Accession #NP_001239335.1) (Uniprot Accession #O15156). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZBTB7B Antibody with the following immunoassay(s):
Western Blot (WB) (Figure 1: Western blot analysis using ZBTB7B mAb against HEK293 (1, 2) cell lysate.)
Immunohistochemistry (IHC) (Figure 2: Immunohistochemical analysis of paraffin-embedded human Breast tissues using anti-ZBTB7B mouse mAb)
Immunofluorescence (IF) (Figure 3: Immunofluorescence analysis of Hela cells using ZBTB7B mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin)
ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
Immunogen: Purified recombinant fragment of human ZBTB7B expressed in E. Coli. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZBTB7B are readily searchable from our website. Different antibodies against the same target such as ZBTB7B may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Connective Tissue, Embryonic Tissue, Intestine, Muscle, Placenta, Skin, Thymus tissues are correlated with this protein.