|The ZBED1 zbed1 (Catalog #MBS151060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZBED1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s ZBED1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
ZBED1 antibody can be used for detection of ZBED1 by Western blot at 1 mug/mL. Researchers should empirically determine the suitability of the ZBED1 zbed1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ZBED1 zbed1 product has the following accession number(s) (GI #15929151) (NCBI Accession #AAH15030) (Uniprot Accession #O96006). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZBED1 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ZBED1 in A549 cell lysate with ZBED1 antibody at 1 μg/mL.)
ZBED1 Antibody: ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.
Immunogen: ZBED1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human ZBED1.
Buffer: ZBED1 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZBED1 are readily searchable from our website. Different antibodies against the same target such as ZBED1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Connective Tissue, Eye, Salivary Gland tissues are correlated with this protein. ZBED1 also interacts with the following gene(s): ZBED3.